Correlated with this decrease in GSH levels, we found that the T2DM group also has significantly higher levels of MDA ( Figures 3B, C ) and higher levels of the proinflammatory cytokine IL-6 ( Figure 3D ) than the healthy group
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Using the chromatographic conditions described in the Section Chromatographic conditions the compounds are eluted in the following order: MESNA (2.62 min), Cys (4.56 min), GSH (4.92 min), NAC (5.09 min), Hcy (5.48 min), MPG (6.02 min), LA (6.54 min), Captopril (7.05 min), N-Hcy-Lys (8.30 min)
Based on the experimental results and literature data on the reactions of GSH with H 2 O 2 and thiyl radicals, a kinetic model of the complex interaction of GSH and H 2 O 2 in an aqueous solution at 37C was proposed